Intravenous montelukast in acute asthma: expensive aminophylline?
نویسندگان
چکیده
منابع مشابه
A randomized controlled trial of intravenous montelukast in acute asthma.
Many patients with acute asthma do not respond adequately to currently accepted therapy, including oxygen, beta-agonists, and corticosteroids. Leukotriene receptor antagonists such as montelukast have demonstrated efficacy in chronic asthma, but their efficacy in acute asthma is unknown. In this randomized, double-blind, parallel-group pilot study, adults with moderate to severe acute asthma re...
متن کاملIntravenous salbutamol and aminophylline in asthma: a search for synergy.
The bronchodilation produced by increasing intravenous doses of aminophylline, salbutamol, and a combination of aminophylline and salbutamol given in random order was determined in 10 stable asthmatics on three consecutive days. On a fourth day, response to placebo injections was determined. Forced expiratory volume in one second (FEV1) was measured at two-minute intervals after each dose until...
متن کاملComparison of intravenous aminophylline and salbutamol in severe asthma.
Severe asthma is the most common respiratory emergency treated in casualty departments of most hospitals. Intravenous aminophylline has been the mainstay of bronchodilator treatment for several years, although sudden death may occur after rapid administration,1 2 and it may be cardiotoxic.3 We thought that a selective adrenoceptor agonist might therefore be worthy of trial, and we report here o...
متن کاملLeukotriene Antagonist Therapy a Randomized, Controlled Trial of Intravenous Montelukast in Acute Asthma
among asthmatic patients. Study Population. Thirty nonsmoking patients with mild/moderate asthma and baseline forced expiratory volume in 1 second values of 70% of predicted values. All patients had experienced no asthma attacks in the previous 2 months and controlled their symptoms with inhaled salbutamol only. Patients did not receive corticosteroids in the 6 months before the study and had n...
متن کاملA randomized placebo-controlled study of intravenous montelukast for the treatment of acute asthma.
BACKGROUND Current treatments for acute asthma provide inadequate benefit for some patients. Intravenous montelukast may complement existent therapies. OBJECTIVE To evaluate efficacy of intravenous montelukast as adjunctive therapy for acute asthma. METHODS A total of 583 adults with acute asthma were treated with standard care during a < or = 60-minute screening period. Patients with FEV(1...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Thorax
سال: 2000
ISSN: 0040-6376
DOI: 10.1136/thorax.55.9.807c